西班牙马德里癌症研究中心博士后岗位

Postdoctoral Position : Madrid, Spain

Institution

Spanish National Cancer Research Centre (CNIO)

Position

Postdoctoral Position

Location

Madrid, Spain

Date Posted

July 17, 2009

Date Expires

November 15, 2009

Tags

crystallography, crystallographer, structural biology, signalling, kinases, drug design, biochemistry

Description

An opening for a post-doctoral position is available starting September 15th at the Structural Biology and Biocomputing Programme of the Spanish National Cancer Research Centre (CNIO) in Madrid, Spain.

The ideal candidate should have a PhD in structural biology, biochemistry or a related field and should have extensive experience in all aspects of protein X-ray crystallography, including protein expression and purification, crystallization, structure determination and refinement. Experience with baculovirus expression is an advantage.

The research focuses on signaling and structural aspects of cell adhesion with particular emphasis on:
1) Employing protein X-ray crystallography in combination with biochemical, functional and FRET studies to elucidate detailed molecular events that regulate cell adhesion.
2) Employing structure based drug design for the discovery of novel anti-cancer drugs that target cell adhesion signaling molecules.

The candidate will work with a team of highly motivated structural biologists and biochemists and collaborate with cell biology and computational groups at the CNIO. The group has a strong expertise in dissecting detailed molecular events that regulate cell adhesion and collaborates with top international research groups to integrate the research into related fields such as growth factor signalling.

The CNIO offers:
• A competitive salary and an attractive benefits package.
• Access to state-of-the-art facilities for robotic crystallization setup, crystal visualization and X-ray diffraction data collection.
• A vibrant, multi-disciplinary and international working environment.
• The opportunity to be part of a European Cancer Research Centre of excellence that successfully combines basic and applied research.
• Situated in one of Europe’s cultural capitals

Contact

Applications can be sent at any time, preferably before 1st of September 2009. Applications with CV and inquiries should be sent by email to the group leader, Dr. Daniel Lietha (liethad@gmail.com). All enquiries and applications will be treated confidentially.

来源：http://www.nature.com/naturejobs/science/jobs/103743-Postdoctoral-Position