英国剑桥Hutchison/MRC肿瘤研究中心博士后岗位

Institution

MRC | Cancer Cell Unit

The Hutchison/MRC Research Centre (http://www.hutchison-mrc.cam.ac.uk) is an established centre for cancer research alongside Addenbrooke’s Hospital in Cambridge. The Centre comprises the MRC Cancer Cell Unit and groups belonging to the University of Cambridge, Department of Oncology.

Position

Post-doctoral Scientist

(MRC Career Development Fellow)

Salary

£25,368 – £26,953 pa

Date Closed

8th October 2008

Description

Applications are invited for a post within the group of Dr Guillermo de la Cueva-Méndez to investigate ways of exploiting prokaryotic toxin Kid and its neutralizing antitoxin Kis in cancer therapy. Kid triggers apoptosis in human cells and, at the right ratios, Kis protects from this effect. Our aim is to design, test and validate strategies to achieve differential modulation of the Kid-to-Kis ratio in cancer cells (to kill them) and normal cells (to protect them).The post-holder will be requested to undertake research aiming to exploit differences between both types of cells (e.g. relative gene copy number, transcription, mRNA stability, translation and/or protein stability) to achieve selective killing of cancer cells using Kid and Kis. Good interpersonal and communication skills are essential and the post-holder should be able to offer multi-disciplinary collaborations.

This Career Development Fellowship is designed to provide post-doctoral training in an excellent research environment for a period of up to 3 years. The starting salary will be between £25,368 – £26,953 pa depending on level of postdoctoral experience. Benefits include a flexible pay and reward policy, good holiday entitlement, MRC final salary pension scheme and access to excellent on-site leisure facilities

Applications for this role should be made online athttp://jobs.mrc.ac.ukquoting reference CCU08/506 please include a full CV including the names of two referees, and a covering letter outlining how you could contribute to the accomplishment of the proposed research objective (relevant literature can be found athttp://www.hutchison-mrc.cam.ac.uk/de_la_Cueva_Mendez.html). If you do not have internet access or experience technical difficulties please call 01793 301260.

Contact

For further information about the MRC visithttp://www.mrc.ac.uk

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