缅因州立大学生殖系统生物学研究博士后岗位

InstitutionWayne State Univeristy School of MedicinePositionPostdoctoral Positions: Reproductive Systems BiologyLocationDetroit Michigan U.S.A.Date PostedSeptember 2nd 2008Date ExpiresDecember 1st 200 ...
Institution

Wayne State Univeristy School of Medicine

Position

Postdoctoral Positions: Reproductive Systems Biology

Location

Detroit, Michigan, U.S.A.

Date Posted

September 2nd 2008

Date Expires

December 1st 2008

Tags

postdoctoral and systems biology

Description

POSTDOCTORAL POSITIONS: REPRODUCTIVE SYSTEMS BIOLOGY

The Krawetz group http://compbio.med.wayne.edu is using the humanprotamine gene cluster, as a model of chromatin mediated genomereprogramming and RNA delivery by sperm to understand early human development.

See:

Linnemann, A.K., Platts, A.E., Doggett, N., Gluch, A., Bode, J. andKrawetz S. A. (2007) Genome wide identification of nuclear matrixattachment regions: an analysis of methods. Biochemical SocietyTransactions. 35:612-617.

Martins, R. P. and Krawetz, S.A. (2007) Decondensing the protaminedomain for transcription. Proceedings of the National Academy ofSciences (U.S.A.) 104:8340-8345.

Krawetz, S.A. (2005) Paternal Contribution: new insights and futurechallenges. Nature Reviews Genetics 6:633-642.

Platts, A.E., Dix, D. J., Chemes, H.E., Thompson, K.E., Goodrich, R.,Rockett, J. C., Rawe, V.Y., Quintana, S., Diamond, M.P., Strader, L.F.and Krawetz, S.A. (2007) Success and failure in human spermatogenesis asrevealed by teratozoospermic RNAs. Human Molecular Genetics. 16:763-773.

As part of an interdisciplinary research team using advanced HTGS, CGH,FISH, Microarray, Real-Time and Computational technologies we willdetermine how chromatin structure and RNA are used to reprogram ourgenome. Self motivated individuals trained in molecular biology,genetics, cytogenetics and/or biochemistry with expertise in HTGS, CGH,FISH and MICROARRAYS are especially encouraged to apply.

Contact

Applicants should forward their cv and three letters of reference to:Dr. S. A. Krawetz, C.S. Mott Center for Human Growth and Development,Wayne State University School of Medicine, 275 E. Hancock, Detroit, MI 48201.
E-mail: steve@compbio.med.wayne.edu.

WSU is an Equal Opportunity/Affirmative Action Employer.

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