德国汉堡分子神经生物学博士后岗位

PositionPostdocInstitutionCentre for Molecular Neurobiology Hamburg (ZMNH) (http://www.zmnh.uni-hamburg.de/)LocationHamburg GermanyDate PostedJan 7th 2008DescriptionWe are looking for a highly motivat ...
Position

Postdoc

Institution

Centre for Molecular Neurobiology Hamburg (ZMNH) (http://www.zmnh.uni-hamburg.de/)

Location

Hamburg, Germany

Date Posted

Jan 7th 2008

Description

We are looking for a highly motivated and experienced cell/molecularbiologist to join a young and dynamic team to study novel signalingmechanisms of receptors in the nervous system. We are studying how thecentral and peripheral nervous system develops and how its integrity ismaintained during aging and toxic insults.
The main focus will be to investigate the function of the receptortyrosine kinase Ret and other cell surface receptors in motor and/ordopaminergic neurons during development and aging. This question can beaddressed using transgenic mouse and fly models, tissue culture, andbiochemical assays.
Literature:
Kramer ER, Knott L, Su F, Dessaud E, Krull C, Helmbacher F, and Klein R(2006). Cooperation between GDNF/Ret and ephrinA/EphA4 Signals forMotor-Axon Pathway Selection in the Limb. Neuron 50: 35-47.
Kramer ER, Aron L, Ramaker GMJ, Seitz S, Zhuang X, Beyer K, Smidt MP andKlein R (2007). Absence of Ret signaling in mice causes progressive andlate degeneration of the nigrostriatal system. PLoS Biol. 5: 616-628.

Contact

Interested candidates should submit a CV, contact details for threereferees and a detailed covering letter to Dr. Edgar Kramer at kramer@zmnh.uni-hamburg.de.

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