德国瓦赫尼根大学招博士后-有机化学

日期:2012-06-16 来源:海外博士后
http://www.pinjiao.com/bsh/guowaiboshihou/2012-06-16/postdoctor127492.html 海外博士后
We are looking for an enthusiastic postdoctoral organic chemist who is willing to offer her/his expertise in polymer and/or surface chemistry for addressing an important issue in health and medicine. There is great interest in the development and validation of handheld (sports) medical devices for continuous monitoring of biomarkers. This project aims at monitoring of lactate in intracellular body fluids as a biomarker for the anaerobic threshold during endurance sports. Other applications will be patient monitoring in intensive care and during surgery as increasing blood lactate level go together with a decreasing survival rate. Monitoring will be done using an array of functionalized microneedles using specific coating techniques. You will synthesize the monomers that will constitute the polymer coating after grafting-from polymerization investigate the surface-bound polymer by a variety of surface-sensitive techniques perform fundamental studies on its structure mechanical and (bio)chemical stability. Finally this information will be used to help construct the specific sensor and optimize its performance.

We are looking for

We are looking for an enthusiastic postdoctoral organic chemist who is willing to offer her/his expertise in polymer and/or surface chemistry for addressing an important issue in health and medicine. There is great interest in the development and validation of handheld (sports) medical devices for continuous monitoring of biomarkers. This project aims at monitoring of lactate in intracellular body fluids as a biomarker for the anaerobic threshold during endurance sports. Other applications will be patient monitoring in intensive care and during surgery, as increasing blood lactate level go together with a decreasing survival rate. Monitoring will be done using an array of functionalized microneedles using specific coating techniques. You will synthesize the monomers that will constitute the polymer coating after grafting-from polymerization, investigate the surface-bound polymer by a variety of surface-sensitive techniques, perform fundamental studies on its structure, mechanical and (bio)chemical stability. Finally, this information will be used to help construct the specific sensor, and optimize its performance.

This is a highly multidisciplinary project in which two universities and four companies collaborate intensively. The project is funded by the regional EFRO innovation program ‘Biomarque’.

We are looking for a postdoc (organic chemist) who will coat microneedles with polymers and sensing molecules, for the specific detection of lactate. Lactate is a biomarker for the anaerobic threshold during endurance sports, and medical circumstances (e.g. during surgery). You will optimize the chemical functionality and stability of the sensor system.



Requirements

For this position we request a PhD in organic chemistry. Hands-on experience with surface chemistry at PhD-level is a prerequisite; experience in polymer chemistry and/or dealing with enzymes is a plus.



We offer

We offer a temporary position with an average working time of 38 hours per week for the period of 2 years. Gross salary


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