德国海德堡大学招聘博士后

The Department of Infectious Diseases, Virology at the University Hospital Heidelberg, Germany offers a

postdoc position (TVLE13) for two years (extension possible)

starting summer 2012

in the laboratory of Prof. Dr. Oliver Fackler.

Replication of major human pathogens such as Human Immunodeficiency Virus Type 1 (HIV-1) is potently suppressed by intrinsic and adaptive immunity strategies of the host. Consequently,HIV-1 has evolved gene products that allow circumvention of these immune responses. One focus of the laboratory is on deciphering the mechanism by which theHIV-1 protein Vpu antagonizes the restriction imposed by the host factor CD317/tetherin to the release of mature virus particles (Goffinet et al., 2009, Cell Host & Microbe; Goffinet et al., 2010, J. Virol.; Schmidt et al., 2011, MBio; Fritz et al., 2012, Virology). Another goal is to understand how theHIV-1 protein Nef undermines mounting of adaptive immunity by interference with immune cell interactions of infected T lymphocytes (Pan et al., 2012, Blood; Stolp et al., 2009, Cell Host & Microbe). Open projects are available in both lines of research.

The successful candidate will have a strong background and practical experience in biochemical analyses of protein interactions and light microscopy. We expect a strong interest in cell biology, virology and immunology, creative and independent research, and a very high level of motivation. We offer interesting research topics with biomedical relevance in a stimulating and interactive scientific environment at an internationally competitive level. Please send your applications with full CV including list of publications and letter of motivation until June 14 to:

Prof. Dr. Oliver T. Fackler

Department of Infectious Diseases, Virology

University Hospital Heidelberg

Im Neuenheimer Feld 324

69120 Heidelberg

phone: +49- (0)6221-56-1322

fax: +49- (0)6221-56-5003

Email:oliver_fackler@med.uni-heidelberg.de

homepagehttp://www.klinikum.uni-heidelberg.de/Fackler.6555.0.html