英国Wolfson中心分子生物学博士后岗位

英国Wolfson中心招收分子生物学博士后,研究脊髓性肌萎缩中SMN蛋白的地位及其与其他蛋白的相互作用。

Institution

Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital and NHS Trust

Position

Postdoctoral Research Scientist

Location

Oswestry, Shropshire, SY10 7AG, UK

Date Posted

August 23

Salary

£19,166-£24,803 (pay award pending)

Description

Applications are invited for a post-doctoral researcher to study the role of SMN protein and its interactions with other proteins in the pathogenesis of spinal muscular atrophy, one of the commonest genetic disorders affecting infants. SMN complexes will be analyzed by mass spectrometry and other molecular techniques (see recent publication in BMC Cell Biology:http://www.biomedcentral.com/1471-2121/8/28).

The successful candidate will have a Ph.D. in biochemistry, biology or related discipline and some knowledge or experience of protein biochemistry, immunochemistry or proteomics.

This full-time post is funded for three years by the Jennifer Trust for SMA; further job details athttp://www.jtsma.org.uk/smn_mass_spectrometry.html.

The successful candidate will join a team of biochemists, cell biologists, pathologists and clinicians in the recently-formed Wolfson Centre for Inherited Neuromuscular Disease, based at the RJAH Orthopaedic Hospital, Oswestry and linked academically to Keele University (www.rjah.nhs.uk/cind). The Centre is well-equipped with two confocal microscopes, two LC-tandem mass spectrometers (ABI 3200 and 4800), tissue culture and DNA cloning facilities.

The Centre has new, modern laboratories and a stress-free, rural location, very close to the mountains of Wales, but is within an hour or so by rail or road of Liverpool, Birmingham and Manchester.

The appointment will be made in the mid-range of NHS Band 5, currently £19,166-£24,803 (pay award pending) and is available from Oct. 1st, 2007.

Contact

Send a CV with email addresses of 3 professional referees to Prof. Glenn Morris (glenn.morris@rjah.nhs.uk) as soon as possible; he will also answer any questions. Closing date 18/9/07

(http://www.rjah.nhs.uk/cind)

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